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Updated: Aug 26, 2025

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression
Published on: January 19, 2019
Neoadjuvant immunotherapy in non-small-cell lung cancer: Times are changing-and fast
Carlos Aguado1, Unai Jiménez Maestre2, Xabier Mielgo-Rubio3
1Department of Medical Oncology, Hospital Universitario Clínico San Carlos, Madrid 28040, Spain. carlos.aguado84@gmail.com.
Abstract:
Recent data from a phase 3 trial have shown that the addition of immunotherapy to neoadjuvant chemotherapy improves event-free survival in patients with non-small-cell lung cancer (NSCLC). This is the first positive phase 3 trial in this setting, although several phase 3 trials are currently investigating the efficacy of neoadjuvant and adjuvant immunotherapy in resectable NSCLC.
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