Related Experiment Video
Updated: Aug 26, 2025

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Factors Contributing to Diagnosis and Prognosis in Sinonasal Malignancies
Wenjing Li1, Jianqiang You1, Haixiang Xue1
1E.N.T. Department, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu 213000, China.
Objectives:
This study was intended to explore and analyze the factors which affect the survival and prognosis of patients with malignant tumors of nasal cavity and sinus.
Methods:
Retrospective analysis was performed on the clinical data of 39 cases of malignant tumors of nasal cavity and sinus that met the requirements of the study. A follow-up study was performed on the patients for more than 36 months. Survival analysis was conducted via the Kaplan-Meier method and log-rank test. Cox regression model was used for multivariate analysis.
Results:
Gender, pathological type, treatment plan, clinical stage, and survival time of patients were different. Clinical stage was substantially related to the survival of patients (P < 0.05), which was an independent factor affecting prognosis.
Conclusions:
Early detection and comprehensive treatment of sinonasal malignancies can improve the prognosis and prolong the survival time of patients.

