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Treatments for Burning Mouth Syndrome: A Network Meta-analysis
R Alvarenga-Brant1, F O Costa2, G Mattos-Pereira2
1Department of Clinical Dentistry, Pathology and Oral Surgery, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Journal of Dental Research
|October 10, 2022
Summary
Clonazepam is likely effective for burning mouth syndrome (BMS) pain relief, meeting the minimal important difference. Other treatments showed low certainty evidence, necessitating more trials comparing them against placebo.
Area of Science:
- Oral Medicine
- Pharmacology
- Evidence-Based Dentistry
Background:
- Burning mouth syndrome (BMS) is a chronic pain condition with limited effective treatments.
- Systematic reviews and meta-analyses are crucial for evaluating therapeutic efficacy in BMS.
Conclusions:
- Only clonazepam currently shows likely efficacy for BMS pain relief against placebo.
- Further high-quality RCTs are needed to confirm findings and explore alternative BMS treatments.

