Related Experiment Video
Updated: Aug 26, 2025

08:07
A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
Published on: January 11, 2018
8.4K
Congenital mandibular coronoid process hyperplasia and associated diseases
1Department of Oral and Maxillofacial Surgery, Affiliated Stomatology Hospital of Kunming Medical University, Kunming, China.
Oral Diseases
|October 10, 2022
Summary
Coronoid process hyperplasia (CPH) causes restricted jaw movement due to enlarged mandibular coronoid processes. Surgical removal (coronoidectomy) effectively improves mouth opening in patients with this condition.
Area of Science:
- Oral and Maxillofacial Surgery
- Genetics
- Pathology
Background:
- Coronoid process hyperplasia (CPH) is an oral and maxillofacial surgical condition characterized by enlarged mandibular coronoid processes, leading to restricted mouth opening.
- Bilateral CPH is less common, often leading to misdiagnosis or delayed treatment.
- The exact etiology of congenital CPH remains unclear, though genetic factors are suspected.
Purpose of the Study:
- To examine the relationship between congenital mandibular CPH and associated diseases.
- To review clinical diagnosis and treatment strategies for CPH-related restricted mouth opening.
Main Methods:
- Case collection from clinical practice.
- Comprehensive literature review on CPH.
Main Results:
- CPH presents as painless, progressive restriction of mouth opening, unilaterally or bilaterally.
- Coronoidectomy demonstrates significant effectiveness in improving mouth opening.
- Congenital CPH is believed to have a genetic basis, though further research is needed.
Conclusions:
- CPH is a significant cause of restricted jaw mobility requiring accurate diagnosis.
- Coronoidectomy is an effective surgical intervention for CPH.
- Understanding the genetic links to congenital CPH is crucial for future research and treatment.
Keywords:
TGF-β/Smad signaling pathwaycongenital related diseasemandibular coronoid process hyperplasiasyndromeMore Related Videos
Related Concept Videos
Mitral Valve Prolapse I: Introduction
32
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
32
Teeth
591
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
591
Mitral Stenosis I: Introduction
27
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
27
Adrenal Gland Disorders
1.7K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
1.7K
Chronic Pharyngitis
4.2K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
4.2K
The Hyoid Bone
2.7K
The hyoid bone is a small U-shaped bone located in the upper neck at the level of the inferior mandible, with its tips pointing posteriorly. It does not directly articulate with any other bone in the body. The hyoid acts as the attachment site for the tongue, the larynx, and the pharynx. It is held in position by a series of small muscles attached from above or below. These muscles help to move the hyoid up/down or forward/back in coordination with movements of the tongue, larynx, and pharynx...
2.7K

