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Monkeypox virus: past and present
Ya-Mei Dou1, Hang Yuan1, Hou-Wen Tian2
1NHC Key Laboratory of Medical Virology and Viral Disease, Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, 155 Changbai Road, ChangPing District, Beijing, 102206, China.
World Journal of Pediatrics : WJP
|October 10, 2022
Summary
Monkeypox is a global health concern with over 45,000 cases reported. Pediatric monkeypox is more severe, necessitating robust public health preparedness and monitoring systems worldwide.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Monkeypox (MPXV) presents a significant global public health challenge.
- Understanding its clinical and epidemiological patterns is crucial.
Purpose of the Study:
- To analyze the current global status of monkeypox.
- To elucidate clinical characteristics and epidemiology.
- To review drug development and vaccine availability.
Main Methods:
- Comprehensive literature review conducted.
- Searched databases: PubMed, Science Direct, Google Scholar.
- Data collected up to July 2022.
Main Results:
- Over 45,000 cases reported by WHO across 92 nonendemic countries by July 2022.
- Most cases occurred in men who have sex with men, particularly those with multiple partners.
- While women and children were infected, the majority of cases were in men.
Conclusions:
- Pediatric monkeypox infection carries a higher risk of severe illness and mortality.
- Antiviral therapy is often required for severe pediatric cases.
- Global monitoring, testing, and emergency preparedness are essential.
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