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Efficacy and safety of tai chi for hyperlipidaemia: a protocol for systematic review and meta-analysis
Weitao Dong1, Feng Zhang1, Daoshi Lian1
1Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine-Shierqiao Campus, Chengdu, Sichuan, China.
Insights
This systematic review evaluates tai chi
Area of Science:
- Cardiovascular Health
- Integrative Medicine
- Metabolic Disorders
Background:
- Hyperlipidaemia prevalence is rising, increasing cardiovascular disease and atherosclerosis risk.
- Tai chi is increasingly studied for hyperlipidaemia management.
- A comprehensive systematic review on tai chi's efficacy and safety for hyperlipidaemia is lacking.
Purpose of the Study:
- To systematically review and evaluate the efficacy and safety of tai chi interventions for patients with hyperlipidaemia.
- To synthesize evidence from randomized controlled trials (RCTs) to inform clinical practice and future research.
Main Methods:
- Systematic literature search of 8 databases (PubMed, Embase, Cochrane, Web of Science, CNKI, CBM, VIP, Wanfang) up to May 2021.
- Inclusion of Chinese and English RCTs on tai chi for hyperlipidaemia.
- Independent study selection, data extraction, and risk of bias assessment using Cochrane risk of bias tool.
- Meta-analysis using RevMan V.5.4 and evidence quality assessment via GRADE approach.
Main Results:
- This section is to be populated upon completion of the meta-analysis.
Conclusions:
- This section is to be populated upon completion of the meta-analysis.
Introduction:
The prevalence of hyperlipidaemia is increasing, and patients with hyperlipidaemia are at increased risk of cardiovascular disease and atherosclerosis. In recent years, there has been a growing number of studies on tai chi for hyperlipidaemia. However, a systematic review on its efficacy and safety is not available. Therefore, this study aims to evaluate the efficacy and safety of tai chi for hyperlipidaemia.
Methods And Analysis:
Four English databases and four Chinese databases will be searched from their inception to May 2021: PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, VIP Database and Wanfang Database. Chinese and English randomised controlled trials related to tai chi for hyperlipidaemia will be included. Two reviewers should independently carry out study selection, data extraction and risk assessment of bias. The risk of bias in the study will be assessed by the Cochrane risk of bias tool. RevMan (V.5.4) statistical software will be applied for meta-analysis. The Grading of Recommendations Assessment, Development and Evaluation system approach will be employed to assess the quality of evidence.
Ethics And Dissemination:
Ethical approval is not required because this protocol will not involve patients' individual information and jeopardise the rights of patients. The meta-analysis result will be reported in peer-reviewed journals or disseminated at related conferences.
Osf Registration Number:
DOI 10.17605/OSF.IO/79D2S.
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