Imaging of pediatric pancreas tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper

Area of Science:

• Pediatric oncology
• Diagnostic imaging
• Radiology

Background:

• Primary pancreatic tumors in children are exceptionally rare.
• Solid pseudopapillary neoplasms and pancreatoblastoma are the most frequent histologic types.
• Standardized imaging protocols for pediatric pancreatic neoplasms are lacking.

Purpose of the Study:

• To outline current imaging modalities for pediatric pancreatic tumors.
• To provide consensus-based recommendations for imaging at diagnosis.
• To establish guidelines for follow-up imaging in pediatric pancreatic neoplasms.

Main Methods:

• Review of current literature on pediatric pancreatic tumor imaging.
• Consensus development among pediatric radiologists and oncologists.
• Evidence-based guideline formulation for imaging techniques and surveillance.

Main Results:

• Detailed description of imaging characteristics for common pediatric pancreatic tumors.
• Specific recommendations for initial diagnostic imaging (e.g., MRI, CT, Ultrasound).
• Guidance on optimal frequency and modality for follow-up imaging based on tumor type and treatment response.

Conclusions:

• Standardized imaging is crucial for accurate diagnosis and monitoring of pediatric pancreatic tumors.
• Consensus recommendations aim to improve diagnostic accuracy and patient management.
• Adherence to these guidelines can optimize surveillance strategies and outcomes for children with pancreatic neoplasms.