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Blood Collection from the American Horseshoe Crab, Limulus Polyphemus
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Blood cell formation in crustaceans

Irene Söderhäll1, Kenneth Söderhäll1

  • 1Department of Organismal Biology, Uppsala University, Norbyvägen 18A, SE-752 36, Uppsala, Sweden.

Fish & Shellfish Immunology
|October 10, 2022
PubMed

In crustacean animals the hemocytes are key players in immunity and of crucial importance for the health of the animals. Hemocytes are mainly produced in the hematopoietic tissue and from there released into the circulation where they finally mature. In this review we summarize the latest findings about crustacean hemocyte formation. The role of the extracellular matrix and crosslinking enzyme transglutaminase is discussed. Moreover, important growth factors, transcriptional regulation and recent findings about inducers of hematopoiesis are covered. Finally, we discuss the use of different markers for classification of crustacean hemocytes.

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