A Value Set for the EQ-5D-Y-3L in the Netherlands
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Published on: June 29, 2019
Bram Roudijk1, Ayesha Sajjad2, Brigitte Essers3
1EuroQol Research Foundation, Rotterdam, The Netherlands. roudijk@euroqol.org.
Insights
This study developed a Dutch value set for the EQ-5D-Y-3L, enabling health economic evaluations in children. This provides crucial data for assessing healthcare interventions for pediatric populations in the Netherlands.
Area of Science:
- Health Economics
- Paediatric Health Outcomes
- Psychometrics
Background:
- Growing need for preference-based health measures in children.
- Lack of a Dutch value set for EQ-5D-Y-3L hinders economic evaluations in the Netherlands.
- This study addresses the gap by collecting child health preferences.
Purpose of the Study:
- To derive a Dutch value set for the EQ-5D-Y-3L instrument.
- To facilitate economic evaluations of healthcare interventions for pediatric populations in the Netherlands.
Main Methods:
- Collected preference data using composite time trade-off (CTTO) and discrete choice experiments (DCE).
- CTTO data from 197 respondents; DCE data from 959 representative Dutch respondents.
- Analyzed DCE data with a mixed-logit model, anchored to QALY scale using CTTO values.
Main Results:
- Generated a Dutch value set for the EQ-5D-Y-3L.
- Health state values ranged from -0.218 to 1.
- Pain/discomfort had the largest weight, followed by emotional state, usual activities, mobility, and self-care.
Conclusions:
- A Dutch value set for EQ-5D-Y-3L has been successfully generated.
- This value set is essential for calculating quality-adjusted life-years (QALYs) in pediatric health economic evaluations.
- Enables evidence-based healthcare policy and resource allocation for children in the Netherlands.
Background And Objective:
There is increasing interest in preference-accompanied measures of health for paediatric populations. The child-friendly EQ-5D version, EQ-5D-Y-3L, is one such instrument, but the lack of a Dutch value set prevents its use in economic evaluations of healthcare interventions in the Netherlands. This study aims at covering this gap by collecting preferences using a standardised protocol for deriving EQ-5D-Y-3L value sets.
Methods:
Composite time trade-off data were collected using videoconferencing interviews, with each respondent completing ten composite time trade-off tasks. Discrete choice experiment data were collected using an online survey, with respondents each completing 15 paired comparisons. Respondents completed these tasks considering what they prefer for a hypothetical 10-year-old child. Discrete choice experiment data were analysed using a ten-parameter mixed-logit model and anchored to the quality-adjusted life-year scale using the mean observed composite time trade-off values.
Results:
The study collected preferences for 197 respondents using composite time trade-off and for 959 respondents using a discrete choice experiment. The discrete choice experiment sample was representative for the Dutch population in terms of age and sex. The level 3 weight for pain/discomfort was the largest, followed by feeling worried, sad or unhappy, usual activities, mobility and self-care. Health state values ranged between -0.218 and 1.
Conclusions:
This study generated a Dutch value set for the EQ-5D-Y-3L, which can be used for the computation of quality-adjusted life-years for economic evaluations of healthcare interventions in paediatric populations.
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