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A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats
Published on: November 11, 2013
[Substitution treatments for opiate-dependent users. An experience of the Integrated Addiction Treatment Center in
Sader Gaye1, Isabelle Malissin2, Macoura Gadji3
1Réanimation médicale et toxicologique, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010, Paris, France - Laboratoire de toxicologie, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010, Paris, France - UMRS-1144 Mécanismes de toxicité et optimisation thérapeutique des psychotropes, Faculté de pharmacie, université Paris Cité, 6 avenue de l'observatoire, 75006, Paris, France - Service d'hématologie biologique et d'oncologie-hématologie (HBOH), Faculté de médecine de pharmacie et d'odontologie, Université Cheikh Anta Diop de Dakar, BP 5005 Dakar-Fann, Sénégal - Centre de prise en charge intégré des addictions de Dakar (CEPIAD), avenue Nelson Mandela, BP 3006, Dakar, Sénégal.
Abstract:
Methadone and buprenorphine are the two maintenance treatments in opiate addicts authorised in France since the end of the 1990's. More recently, some African countries such as Senegal have implemented a new health policy focused on reducing the risks by encouraging the use of methadone as maintenance treatment. The objectives of maintenance therapy are to reduce morbidity and mortality related to the consumption of heroin and other street opioids, to promote the integration of drug users into the healthcare system, and more generally, to improve their social integration. However, this strategy might have limitations in practice. Here, we report the experience of the Integrated Addiction Treatment Center in Dakar, Senegal, and discuss ethical considerations at both the individual and collective levels, which may improve care of opiate-dependent users in practice, especially in Africa.
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