Related Experiment Video
Updated: Aug 26, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
Minimal information for reporting a genomics experiment
Kostiantyn Dreval1,2, Paul C Boutros3, Ryan D Morin1,2
1Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada.
Abstract:
Exome and genome sequencing has facilitated the identification of hundreds of genes and other regions that are recurrently mutated in hematologic neoplasms. The data sets from these studies theoretically provide opportunities. Quality differences between data sets can confound secondary analyses. We explore the consequences of these on the conclusions from some recent studies of B-cell lymphomas. We highlight the need for a minimum reporting standard to increase transparency in genomic research.
Related Concept Videos
Genome Size and the Evolution of New Genes
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Genomics

