Methods for developing and reporting living evidence synthesis

Identify currently methodological aspects proposed for planning, conducting, and reporting living evidence (LE) synthesis. Develop a preliminary checklist of key LE synthesis elements.

A survey of methodological articles describing or analyzing methods for the design, conduction, or reporting of LE synthesis.

Twelve methodological articles were identified and analyzed. Key elements were related to: i) definition of LE and characteristics of LE synthesis, ii) methods and tools for the living process, iii) new evidence integration (methods and considerations), iv) updates dissemination and publication, v) revisiting living parameters, and vi) protocol considerations for LE synthesis.

This survey displays basic methodological concepts that can drive the development of LE synthesis and identifies specific aspects with opportunities for development. The potential impact of the LE approach calls for a change in the current evidence synthesis updating processes to more open, collaborative, transparent, and efficient systems. LE approaches also challenge journal editors to shift toward more efficient processes for synthesis update dissemination, which minimizes the risks of reliability of published information.