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scNanoATAC-seq: a long-read single-cell ATAC sequencing method to detect chromatin accessibility and genetic variants

Yuqiong Hu1,2, Zhenhuan Jiang1,2,3, Kexuan Chen1,2

  • 1Biomedical Pioneering Innovation Center, School of Life Sciences, Peking University, Beijing, China.

Cell Research
|October 11, 2022
PubMed
Abstract

No abstract available in PubMed .

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...