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Benzodiazepines and Related Drugs in Orthopaedics
Bryan A Hozack1, Justin M Kistler, Alexander R Vaccaro
1Rothman Orthopaedic Institute, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
The Journal of Bone and Joint Surgery. American Volume
|October 12, 2022
Summary
Benzodiazepines are widely prescribed for various conditions. Orthopaedic surgeons must understand their risks, especially concerning opioid use and abuse, due to patient prevalence.
Area of Science:
- Pharmacology
- Orthopaedic Surgery
- Public Health
Background:
- Benzodiazepines are globally prevalent medications used for anxiety, insomnia, seizures, and muscle spasms.
- Concerns regarding benzodiazepine dependence and abuse are rising, particularly alongside the opioid crisis.
- Benzodiazepines can exacerbate the risks associated with prolonged opioid use and misuse.
Purpose of the Study:
- To inform orthopaedic surgeons about the widespread use of benzodiazepines.
- To highlight the specific risks and adverse effects of benzodiazepines in orthopaedic patients.
- To underscore the importance of awareness regarding benzodiazepine prescriptions in this population.
Main Methods:
- Literature review on benzodiazepine prevalence and usage.
- Analysis of benzodiazepine's role in orthopaedic patient care.
- Examination of risks, including dependence, abuse, and interaction with opioids.
Main Results:
- Benzodiazepines are frequently prescribed to orthopaedic patients.
- Concurrent use of benzodiazepines and opioids increases risks.
- Surgeons require knowledge of benzodiazepine pharmacology and patient risks.
Conclusions:
- Orthopaedic surgeons must be aware of benzodiazepine prescription rates and associated risks.
- Understanding benzodiazepine's potential to worsen opioid dependence is critical.
- Informed prescribing practices are essential for patient safety in orthopaedics.
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