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Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes
Published on: September 15, 2023
Overview of Aedes aegypti and Use in Laboratory Studies
Margot P Wohl1, Conor J McMeniman2,3
1W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA.
Abstract:
The yellow fever mosquito Aedes aegypti is a prolific disease vector. This mosquito has been the subject of scientific investigation for more than a century. Continued research into Aedes aegypti biology is crucial for understanding how to halt the suite of major arthropod-borne viral diseases this mosquito transmits. Here, we provide an introductory overview of Aedes aegypti life cycle; evolutionary history, biology, and ecology; genetics and sex differences; vector competence; and laboratory colonization and considerations for rearing this robust mosquito species for use in laboratory research.

