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Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Outcomes of surgical treatment on type A acute aortic dissection accompanied with coronary artery involvement
Wei Qin1, Rui Fan2, Jiankai Wang1
1Department of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Insights
Coronary artery bypass grafting (CABG) and local coronary repair offer similar long-term survival for type A acute aortic dissection (AAD) patients with coronary artery involvement. These surgical strategies effectively manage blood flow restoration in complex cardiovascular cases.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Vascular Surgery
Background:
- Acute aortic dissection (AAD) involving coronary arteries (CA) presents a high mortality risk.
- Surgical repair of the aorta requires strategies to restore CA blood flow.
- Coronary artery bypass grafting (CABG) and local coronary repair are primary surgical options.
Purpose of the Study:
- To compare operative and long-term outcomes of CABG versus local coronary repair in type A AAD patients with CA involvement.
- Evaluate the effectiveness of different surgical approaches for managing coronary complications during aortic repair.
Main Methods:
- Retrospective review of 148 type A AAD patients with CA involvement (2001-2021).
- Patients underwent either aortic repair with concomitant CABG (Group I) or local coronary repair (Group II).
- Comparison of perioperative complications, hospital mortality, and long-term survival rates.
Main Results:
- Group I (CABG) had more patients with acute myocardial ischemia and complex CA lesions (types B/C) than Group II (local repair).
- Postoperative acute kidney injury was significantly higher in Group I (34.5%) compared to Group II (8.9%).
- Hospital mortality and long-term survival rates showed no statistically significant difference between the groups.
Conclusions:
- Both CABG and local coronary repair are viable options for type A AAD with CA involvement.
- The choice of strategy should consider the specific type of CA involvement.
- Both approaches yield comparable long-term survival outcomes.
Background:
Coronary artery (CA) involvement due to acute aortic dissection (AAD) is a catastrophic cardiovascular disease with high mortality. Two main surgery strategies, local coronary repair and coronary artery bypass grafting (CABG) can be applied to reestablish the blood flow in the aortic repair. This study was to evaluate the operative and long-term outcomes of type A AAD patients, who received aortic dissection repair plus CABG or local coronary repair.
Method:
We reviewed our database and screened 148 type A AAD patients with CA involvement from January 2001 to December 2021. Local coronary repair or CABG was performed concomitantly on these enrolled patients.
Results:
At the time of aortic repair, there were 58 patients with concomitant CABG (Group I) and 90 patients with local coronary repair (Group II). The basal characteristics of these two groups had no difference, except for acute myocardial ischemia (AMI) and CA involvement type. 45 patients with AMI in Group I, but none in Group II (P < 0.001). There was a higher frequency of type B and C lesions of CA involvement in Group I than that in Group II (P < 0.001). There was no difference in surgical procedures and complications, except for postoperative acute kidney injury (AKI) (34.5% vs. 8.9%, P < 0.001). Hospital mortality in Group I was higher than that in Group II, but without statistical difference (20.7% vs. 11.1%, P = 0.155). No significant difference was obtained in long-term survival rate between the two groups (82.5 ± 4.8% vs. 81.2 ± 6.9%, P = 0.19).
Conclusion:
CABG and local coronary repair suits different types of CA involvement, and their effects on perioperative results and long-term survival for type A AAD patients with CA involvement are equal.
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