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Updated: Aug 26, 2025

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

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A Study of Vitamin D and Its Correlation With Severity and Complication of Congestive Heart Failure: A Systematic

Mohammad Hazique1, Kokab Irfan Khan2, Prasana Ramesh1

  • 1Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Cureus
|October 13, 2022
PubMed

Insights

Vitamin D deficiency is linked to worse outcomes in heart failure patients. Supplementation may lower inflammation and improve cardiac function and quality of life.

Area of Science:

  • Cardiology
  • Endocrinology
  • Nutritional Science

Background:

  • Vitamin D plays a role in cardiovascular health and hypertension.
  • Low vitamin D levels are associated with poorer outcomes in heart failure (HF) patients.
  • Vitamin D deficiency is common in patients with precursor conditions like diabetes and atherosclerosis.

Purpose of the Study:

  • To evaluate the association between vitamin D and congestive heart failure (CHF).
  • To determine the effects of vitamin D supplementation on cardiac function and inflammatory markers in CHF patients.

Main Methods:

  • Systematic review of studies published between January 2012 and December 2022.
  • Searches conducted in PubMed/PMC, Medline, and Cochrane Library.
  • Adherence to PRISMA 2020 guidelines, including quality appraisal of 13 retained articles (10 RCTs, 3 observational studies).

Main Results:

  • Vitamin D supplementation reduced serum inflammatory markers in CHF patients.
  • Vitamin D treatment improved cardiac function and inhibited ventricular remodeling.
  • Supplementation enhanced the quality of life for patients with CHF.

Conclusions:

  • Vitamin D supplementation shows potential benefits for patients with congestive heart failure.
  • Further research is needed to clarify the role of vitamin D in improving ventricular remodeling.
  • Maintaining adequate vitamin D levels may be important for managing cardiovascular health in HF patients.

Keywords:
cardiac remodellingcongestive heart faiulreinflammationlow level of vitamin d serum.myocardial infarenovascular hypertensionvitamin d supplementation

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