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Primary Appendiceal Adenocarcinoma Masquerading as Acute Appendicitis: A Case Report
Grace Young1, Zachary Brennan2, Rafael Figueroa3
1Surgery, A.T. Still University - Kirksville College of Osteopathic Medicine, Kirksville, USA.
Cureus
|October 13, 2022
Summary
Primary appendiceal adenocarcinoma is rare and often found incidentally. This case highlights the need for vigilance in older adults with atypical appendicitis symptoms, as neoplasm may be present.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Primary adenocarcinoma of the appendix is an uncommon malignancy.
- Incidental discovery during abdominal procedures is frequent.
- Appendiceal neoplasms can present with varied clinical signs.
Observation:
- A 69-year-old male presented with atypical symptoms suggestive of acute appendicitis.
- Symptoms included intermittent right lower quadrant pain without fever or anorexia.
- The patient underwent a laparoscopic appendectomy for presumed appendicitis.
Findings:
- Histopathologic examination of the appendix revealed invasive adenocarcinoma.
- The diagnosis was incidental, discovered post-operatively.
- This underscores the challenge in differentiating appendicitis from appendiceal neoplasm based on initial presentation.
Implications:
- Clinicians should consider appendiceal neoplasm in older patients with atypical appendicitis symptoms.
- Enhanced diagnostic vigilance is crucial for early detection of rare appendiceal cancers.
- Prompt histopathological analysis of appendectomy specimens is vital for accurate diagnosis and management.

