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Nail Changes in COVID-19: A Cross Sectional Study From India
Chander Grover1, Sushobhan Saha1, Deepika Pandhi1
1Department of Dermatology and STD, University College of Medical Sciences and GTB Hospital, Delhi, India.
Indian Dermatology Online Journal
|October 13, 2022
Summary
COVID-19 commonly causes nail changes, including red half-moons and leukonychia. These common nail manifestations in patients with coronavirus disease 2019 reflect systemic illness and potential complications.
Area of Science:
- Dermatology
- Infectious Diseases
- Internal Medicine
Background:
- Isolated reports of nail changes associated with COVID-19 have been documented.
- Nail manifestations can serve as indicators of systemic illness.
Purpose of the Study:
- To investigate the prevalence and types of nail changes in hospitalized patients with moderate to severe COVID-19.
- To correlate nail findings with disease status and patient outcomes.
Main Methods:
- A cross-sectional study evaluated nail findings in 43 adult COVID-19 patients.
- Nail changes in fingernails and toenails were documented, and compared statistically.
- Disease status, laboratory tests, and treatments were recorded.
Main Results:
- Common fingernail changes included red half-moon sign (32.5%) and nail bed erythema (34.8%).
- Apparent leukonychia (46.5%) and distal brown discoloration (51.1%) were most frequent in toenails.
- Nail changes were statistically more frequent in toenails than fingernails and correlated with systemic involvement.
Conclusions:
- Nail changes are a common finding in COVID-19 patients.
- Observed nail alterations reflect the systemic nature of the illness.
- Nail changes may indicate underlying complications of COVID-19.
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