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Drug-Related Problems in Bariatric Surgery: a Retrospective Study
Yuping Wang1, Jie Zhu2,3,4,5, Luchen Shan6
1Department of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Obesity Surgery
|October 13, 2022
Summary
Drug-related problems (DRPs) are common after bariatric surgery, particularly with perioperative antibiotics. Clinical pharmacists can help reduce these issues and improve patient recovery.
Area of Science:
- Pharmacology
- Surgical Outcomes
- Patient Safety
Background:
- Bariatric surgery rates are increasing globally.
- Drug-related problems (DRPs) are a growing concern in this patient population.
Purpose of the Study:
- To determine the incidence and characteristics of DRPs in patients undergoing bariatric surgery.
- To identify factors associated with DRPs in this cohort.
Main Methods:
- Retrospective analysis of medication records for 347 bariatric surgery patients (Jan 2019-Dec 2020).
- DRPs classified using PCNE v9.0; severity rated by NCC MERP.
- Statistical analysis included t-tests, chi-square, and ANOVA.
Main Results:
- 760 DRPs identified (average 2.19 per patient).
- Most common DRPs involved perioperative antibiotics (29.47%), hepatoprotection (25.62%), and proton-pump inhibitors (PPIs) (14.34%).
- DRPs linked to older age, fewer concomitant surgeries, longer postoperative fasting time (PFT), and more comorbidities.
Conclusions:
- High incidence of DRPs in the perioperative period of bariatric surgery.
- Fewer concomitant surgeries and longer PFT are risk factors for DRPs.
- Clinical pharmacist involvement is crucial for medication monitoring to enhance recovery.
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