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Updated: Aug 26, 2025

Murine Kidney Transplant Technique
Published on: October 20, 2015
Kidney support for babies: building a comprehensive and integrated neonatal kidney support therapy program
Tahagod H Mohamed1,2, Jolyn Morgan3, Theresa A Mottes4
1Division of Nephrology and Hypertension, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA. Tahagod.Mohamed@Nationwidechildrens.org.
Kidney support therapy (KST) in neonates has evolved with new devices and filters, expanding treatment options. Establishing a neonatal KST program requires a multidisciplinary team and institutional support for safe and effective care.
Area of Science:
- Pediatric Nephrology
- Neonatal Intensive Care
- Critical Care Medicine
Background:
- Kidney support therapy (KST), including peritoneal dialysis (PD), intermittent hemodialysis (iHD), and continuous kidney support therapy (CKST), treats severe acute kidney injury (AKI) and kidney failure.
- Extracorporeal KST in neonates traditionally faced challenges due to small patient size and device limitations, making PD the most common modality.
- Recent advancements in CKST machines and filters designed for neonates have improved safety and efficacy, expanding treatment options.
Conclusions:
- Advancements in KST technology are transforming neonatal care for AKI and kidney failure.
- Developing a neonatal KST program requires careful planning, expert teams, and quality improvement initiatives.
- These evolving treatment options necessitate a recalibration of the benefit:risk assessment for neonatal KST.
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