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2022 European Thyroid Association Guidelines for the management of pediatric thyroid nodules and differentiated
Chantal A Lebbink1, Thera P Links2, Agnieszka Czarniecka3
1Wilhelmina Children's Hospital and Princess Máxima Center, Utrecht, The Netherlands.
Insights
European experts developed new guidelines for pediatric thyroid nodules and differentiated thyroid carcinoma (DTC) management. These recommendations address unique pediatric characteristics, ensuring specialized care for children with these conditions.
Area of Science:
- Endocrinology
- Oncology
- Pediatrics
Background:
- No existing European guidelines for pediatric thyroid nodules and differentiated thyroid carcinoma (DTC).
- Pediatric DTC exhibits distinct clinical, molecular, and pathological features compared to adults, necessitating tailored recommendations.
- Need for specific guidance for healthcare professionals managing pediatric thyroid conditions.
Framework:
- Developed by a European expert panel from diverse disciplines (endocrinology, pathology, surgery, genetics, oncology).
- Utilized the 2015 American Thyroid Association Pediatric Guideline as a foundational framework.
- Identified areas of discordance and formulated clinical questions for guideline development.
Implementation:
- Recommendations formulated based on the latest evidence and expert consensus.
- Emphasizes the requirement for specialized care in experienced centers for children with thyroid nodules or DTC.
- Provides guidance for informed decision-making among healthcare professionals, patients, and parents.
Implications:
- Establishes the first European recommendations for pediatric thyroid nodule and DTC management.
- Aims to standardize and improve the quality of care for children with these conditions across Europe.
- Facilitates collaborative decision-making for diagnosis, treatment, and follow-up of pediatric thyroid disorders.
Abstract:
At present, no European recommendations for the management of pediatric thyroid nodules and differentiated thyroid carcinoma (DTC) exist. Differences in clinical, molecular, and pathological characteristics between pediatric and adult DTC emphasize the need for specific recommendations for the pediatric population. An expert panel was instituted by the executive committee of the European Thyroid Association including an international community of experts from a variety of disciplines including pediatric and adult endocrinology, pathology, endocrine surgery, nuclear medicine, clinical genetics, and oncology. The 2015 American Thyroid Association Pediatric Guideline was used as framework for the present guideline. Areas of discordance were identified, and clinical questions were formulated. The expert panel members discussed the evidence and formulated recommendations based on the latest evidence and expert opinion. Children with a thyroid nodule or DTC require expert care in an experienced center. The present guideline provides guidance for healthcare professionals to make well-considered decisions together with patients and parents regarding diagnosis, treatment, and follow-up of pediatric thyroid nodules and DTC.
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