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Related Experiment Videos

Geographic tongue in two siblings.

Y Kuramoto, T Tadaki, N Hatchome

    Dermatologica
    |January 1, 1987
    PubMed
    Summary

    Geographic tongue may present in two forms: one linked to atopy and another as an oral sign of pustular psoriasis. Both types share similar histopathological features, suggesting a potential link between these conditions.

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    Area of Science:

    • Oral Medicine
    • Dermatology
    • Genetics

    Background:

    • Geographic tongue (benign migratory glossitis) is a common, benign inflammatory condition of the oral mucosa.
    • Its etiology is largely unknown, but associations with atopy and certain genetic factors have been suggested.
    • Pustular psoriasis is a severe form of psoriasis with distinct clinical and histopathological features.

    Observation:

    • Two sisters, aged 6 and 4, presented with geographic tongue.
    • The elder sister had atopic dermatitis and nail changes; their father had fissured tongue.
    • Histological examination of the elder sister's geographic tongue revealed features similar to oral lesions in pustular psoriasis.

    Findings:

    • The study suggests a potential classification of geographic tongue into two types based on clinical presentation and associations.
    • Type 1: Commonly observed in individuals with atopy.
    • Type 2: Manifests as an oral manifestation of pustular psoriasis, despite similar histopathological findings to Type 1.

    Implications:

    • This classification may aid in understanding the diverse etiologies of geographic tongue.
    • Recognizing geographic tongue as a potential oral manifestation of pustular psoriasis could lead to earlier diagnosis and management of systemic disease.
    • Further research is warranted to elucidate the shared histopathological pathways and genetic underpinnings of these conditions.

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