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The Incidence and Risk Factors for Dry Eye After Pediatric Strabismus Surgery
Yun Wang1, Xiao-Jiao Tang1, Qing Liu1
1Department of Ophthalmology, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, 136, Zhongshan 2nd Rd, Yuzhong District, Chongqing, 400014, China.
Insights
Dry eye is common after pediatric strabismus surgery, affecting nearly half of patients initially. Children with lower preoperative tear breakup time (BUT) face a higher risk of developing post-surgery dry eye.
Area of Science:
- Ophthalmology
- Pediatric Surgery
- Ocular Surface Disease
Background:
- Pediatric strabismus surgery is a common procedure.
- Post-surgical dry eye can impact patient recovery and visual outcomes.
- Understanding the incidence and risk factors for dry eye is crucial.
Purpose of the Study:
- To determine the incidence of dry eye following pediatric strabismus surgery.
- To identify risk factors associated with post-operative dry eye.
Main Methods:
- Prospective cohort study involving children aged 5-12 years undergoing strabismus surgery.
- Ocular surface assessments performed pre-operatively and at 1, 4, and 8 weeks post-surgery.
- Key outcome measures included dry eye incidence and tear breakup time (BUT).
Main Results:
- The incidence of dry eye was 47.62% at 1 week, decreasing to 10.71% by 4 weeks and 0% by 8 weeks.
- Lower preoperative tear breakup time (BUT) was significantly associated with a higher incidence of dry eye (OR 0.647, P≤0.01).
- Tear film instability was identified as a more prevalent issue than deficient aqueous tear production.
Conclusions:
- Dry eye is a frequent complication after pediatric strabismus surgery.
- Preoperative tear film instability, indicated by low BUT, is a significant risk factor.
- Early identification of children with low BUT can help predict and manage post-operative dry eye.
Introduction:
This study aimed to investigate the incidence and risk factors for dry eye after pediatric strabismus surgery.
Methods:
Children aged 5-12 years who underwent strabismus surgery were included in this single-center, prospective, cohort study. The ocular surface assessments were conducted 1 day before and 1, 4, and 8 weeks after surgery. The main outcome measures were the incidence of dry eye after strabismus surgery and associated risk factors.
Results:
A total of 84 eyes (48 children) that underwent strabismus surgery were included in the study. The mean age at surgery was 7.21 years. The incidence of dry eye was 47.62% at 1 week, 10.71% at 4 weeks, 0% at 8 weeks after surgery. The preoperative tear breakup time (BUT) was lower in the dry eye group than that in the non-dry eye group (P ≤ 0.01). The univariate analysis showed that preoperative BUT was significantly associated with the incidence of dry eye after pediatric strabismus surgery (odds ratio [OR] 0.647, confidence interval [CI] 0.503-0.833, P ≤ 0.01).
Conclusions:
Dry eye commonly occurs after pediatric strabismus surgery. Tear film instability is more common than deficient aqueous tear production in patients with dry eye after surgery. Children with a low preoperative BUT are more likely to develop dry eye after strabismus surgery.
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