[Animal experiment studies of neurolysis of peripheral nerves]

This animal study is intended to give information about nerve lesions caused by operation after using different kinds of neurolysis. It can be stated that simple nerve mobilisation leads to iatrogenic damage. The more neurolysis penetrates between the fascicular structure of the nerve, the higher the risk of lesion. After experimental internal neurolysis one can see a considerable atrophy of muscle as opposed to experimental external neurolysis. In the histochemical reactions, normal muscle and muscle after external neurolysis show a mosaic pattern of their fibre types. "Fibre type grouping", seen after internal neurolysis, refers to a phenomenon typical for a previously denervated and subsequently reinnervated muscle. Clearly, there is the possibility of regeneration after iatrogenic nerve damage caused by neurolysis.