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Prognostic Value of Coronary Calcium Score in Asymptomatic Individuals: A Systematic Review

Liberatore Tramontano1, Bruna Punzo1, Alberto Clemente2

  • 1IRCSS SYNLAB SDN, 80143 Naples, Italy.

Journal of Clinical Medicine
|October 14, 2022
PubMed

Insights

The coronary artery calcium (CAC) score accurately predicts cardiac event risk in asymptomatic individuals. This score aids in personalized preventive therapy and managing risk factors for better cardiovascular health.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Medical Imaging

Background:

  • Asymptomatic individuals often carry a high risk for coronary artery disease (CAD) and cardiac events.
  • Updated guidelines and technology exist, yet risk stratification remains crucial.

Purpose of the Study:

  • To systematically review and assess the prognostic value of coronary artery calcium (CAC) scoring in asymptomatic individuals.
  • To determine the clinical significance of CAC scores for risk management and personalized prevention.

Main Methods:

  • A systematic literature search was conducted following PRISMA guidelines, focusing on studies published since 2010.
  • Included articles evaluated the prognostic value of CAC scores in asymptomatic populations.
  • Study quality was assessed using the QUIPS tool.

Main Results:

  • A total of 45 articles were selected for review.
  • Twenty-five studies specifically evaluated the prognostic value of CAC scores in asymptomatic subjects.
  • CAC scoring demonstrated valuable prognostic information for predicting CAD risk.

Conclusions:

  • Coronary artery calcium (CAC) scoring is a clinically significant tool for risk stratification in asymptomatic individuals.
  • CAC scores facilitate personalized preventive strategies and effective risk factor management.
  • The findings support the use of CAC scoring for identifying individuals who may benefit from early intervention.

Keywords:
agatstoncalcium scorecoronary artery diseaseprimary preventionrisk assessment

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