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Technical Tips and Tricks after 10 Years of HyFoSy for Tubal Patency Testing
Roxana-Elena Bohîlțea1,2, Bianca-Margareta Mihai2, Cătălina-Diana Stănică1
1Department of Obstetrics and Gynaecology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Journal of Clinical Medicine
|October 14, 2022
Summary
Hysterosalpingo-foam sonography (HyFoSy) is a minimally invasive infertility test that effectively evaluates tubal patency. This study found HyFoSy to be well-tolerated, with a significant pregnancy rate achieved post-procedure.
Area of Science:
- Reproductive Medicine
- Medical Imaging
- Gynecology
Background:
- Hysterosalpingo-foam sonography (HyFoSy) is increasingly utilized for evaluating tubal patency in infertile patients.
- It is recognized as a feasible, well-tolerated, and minimally invasive diagnostic method.
Purpose of the Study:
- To share technical insights and practical tips for performing HyFoSy.
- To enhance procedure feasibility and patient comfort (pain reduction).
- To assess the pregnancy-obtaining rate following HyFoSy.
Main Methods:
- An observational study involving 672 infertile patients undergoing HyFoSy.
- Evaluation of tubal pathway, patency, and patient-reported pain levels.
- A follow-up questionnaire assessed pregnancy rates at 3 months and beyond.
Main Results:
- The median patient age was 33.5 years; 61.16% of procedures occurred between days 8-10 of the menstrual cycle.
- Tubal patency was confirmed in 86% (bilateral) and 11% (unilateral) of cases.
- 75% reported minimal or tolerable pain; 10.86% achieved natural pregnancy within 3 months post-HyFoSy.
Conclusions:
- HyFoSy is a valuable, user-friendly, and largely painless tool for female infertility assessment.
- It complements transvaginal ultrasonography by visualizing tubal patency, regularity, and occlusion.
- HyFoSy should be considered a first-line infertility investigation alongside transvaginal ultrasound.

