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Intermittent Fasting-A Healthy Dietary Pattern for Diabetic Nephropathy
Ming Yang1,2, Wei Chen2, Liyu He2
1Department of Nutrition, Xiangya Hospital, Central South University, Changsha 410008, China.
Nutrients
|October 14, 2022
Summary
Intermittent fasting (IF) shows potential in managing diabetic nephropathy (DN) by improving risk factors and renal injury. This dietary strategy may offer a novel approach to prevent and delay DN progression in diabetic patients.
Area of Science:
- Nephrology
- Metabolic Diseases
- Dietary Interventions
Background:
- Diabetic nephropathy (DN) is a severe complication of diabetes, characterized by systemic metabolic disorders and progressive kidney damage.
- Intermittent fasting (IF) has demonstrated benefits in various metabolic and cardiovascular diseases, but its specific role in DN requires further investigation.
Purpose of the Study:
- To review current research on the relationship between intermittent fasting (IF) and the progression of diabetic nephropathy (DN).
- To discuss the potential mechanisms through which IF may mitigate renal injury in DN.
- To evaluate IF as a potential strategy for preventing and delaying DN progression.
Main Methods:
- Literature review of studies investigating intermittent fasting (IF) and diabetic nephropathy (DN).
- Analysis of the impact of IF on risk factors associated with DN progression.
- Exploration of mechanistic pathways linking IF to improved renal outcomes in DN models.
Main Results:
- Intermittent fasting (IF) is associated with improvements in key risk factors for diabetic nephropathy (DN) progression.
- Evidence suggests IF can ameliorate renal injury through various cellular and molecular mechanisms.
- IF demonstrates potential in preclinical and clinical settings for managing DN.
Conclusions:
- Intermittent fasting (IF) emerges as a promising dietary strategy for managing diabetic nephropathy (DN).
- Further research is warranted to optimize IF protocols for DN treatment and prevention.
- IF may represent a valuable therapeutic option to delay the progression of kidney disease in diabetic individuals.
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