A Report of Haemophilus influenzae Bacteremia With Acute Pelvic Inflammatory Disease
Related Experiment Video
Updated: Aug 25, 2025

Author Spotlight: Enhancing Women's Chronic Pelvic Pain Management Through Acupoint Catgut Embedding
Published on: May 3, 2024
Daphne-Dominique H Villanueva1, Jordan P Staton2, Asmita A Gupte3,4
1Division of Infectious Diseases, West Virginia University School of Medicine, Morgantown, USA.
Abstract:
Sexually-transmitted organisms that frequently originate from the flora of the lower genital tract are often implicated in pelvic inflammatory disease (PID). Haemophilus influenzae, a pathogen found primarily in the upper respiratory tract, has been rarely associated with PID. Here we report a case of a young woman with PID whose blood cultures grew H . influenzae biotype II, a reminder that the endometrium can be the source of systemic H. influenzae infection when no typical primary focus is found.
Insights
Pelvic inflammatory disease (PID) is usually caused by genital tract organisms. This case shows Haemophilus influenzae, typically a respiratory pathogen, can cause PID originating from the endometrium.
Area of Science:
- Microbiology
- Infectious Diseases
- Gynecology
Background:
- Pelvic inflammatory disease (PID) is a common gynecological infection.
- It is typically caused by ascending bacteria from the lower genital tract, including sexually transmitted organisms.
- Haemophilus influenzae is primarily known as a respiratory tract pathogen and rarely associated with PID.
Observation:
- A case study of a young woman presenting with PID is described.
- Blood cultures from the patient revealed the presence of H. influenzae biotype II.
Findings:
- This case demonstrates a rare instance of H. influenzae causing PID.
- The findings suggest that the endometrium can serve as a primary source for systemic H. influenzae infections.
Implications:
- This challenges the traditional understanding of PID etiology.
- It highlights the importance of considering less common pathogens like H. influenzae in PID cases, especially when a typical source is absent.
- Clinicians should be aware of the endometrium as a potential origin for systemic H. influenzae infections.
Related Concept Videos
Acute Pyelonephritis I: Introduction
Acute Pyelonephritis II: Diagnostic Studies and Management
Urinary Tract Infection II: Pathophysiology
Sexually Transmitted Infections
Urinary Tract Infection I: Introduction
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.

