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Evaluation of Complication Rates of Free Flap Reconstruction in Pediatric Patients
Omar Allam1, Rema Shah1, Joshua B Cadwell2
1Department of Surgery, Yale University School of Medicine, New Haven, CT, USA.
Insights
Pediatric free flap reconstruction is safe and effective across various flap types and locations. This national study reveals complication rates and identifies risk factors, informing future pediatric reconstructive surgery.
Area of Science:
- Plastic Surgery
- Pediatric Surgery
- Reconstructive Surgery
Background:
- Limited data exists on free flap efficacy in pediatric patients.
- This study addresses a gap in understanding complication rates in pediatric free flap reconstruction on a national level.
Purpose of the Study:
- To analyze complication rates of pediatric free flap reconstruction.
- To identify predictors of flap complications or failure in children.
Main Methods:
- Utilized the National Surgical Quality Improvement Program database (2012-2018).
- Stratified pediatric free flap cases by flap type, recipient location, and demographics.
- Employed chi-square, univariate, and multivariate analyses to assess complication rates and predictors.
Main Results:
- Compared to bone flaps, skin, muscle, and osteocutaneous flaps showed increased nonbleeding complications.
- Trunk and upper extremity flaps had higher odds of bleeding complications than head-and-neck flaps.
- Older pediatric patients (5-17 years) had greater rates of bleeding complications; reoperation rates ranged from 3.6%-4.7%.
Conclusions:
- Free flap reconstruction is safe and effective in the pediatric population.
- Complication risks vary by flap type, anatomic location, and patient age.
- Findings provide valuable insights for optimizing pediatric reconstructive surgery outcomes.
Introduction:
While there is extensive literature investigating surgical outcomes in free flaps for adults, there is a dearth of information on the efficacy of flap use in the pediatric population. This study is the first to measure complication rates following pediatric free flap reconstruction on a national level.
Methods:
All pediatric free flap cases between 2012 and 2018 were identified and stratified by type of flap using current procedural terminology codes assigned to the primary procedure in the National Surgical Quality Improvement Program database. Each entry included the recipient location of the flap, postoperative complications, and demographics. Chi-square analysis was used to compare complication rates across various flap groupings. In addition, univariate and multivariate analyses were used to identify independent predictors of flap complications or failure.
Results:
Multivariate regression analysis demonstrated that compared to bone flaps, there is increased risk of nonbleeding complications in skin (Odds Ratio (OR) =7.7, P = 0.029), muscle (OR = 10.6, P = 0.012), and osteocutaneous flaps (OR = 10.8, P = 0.018). Flap of the trunk (OR = 40.9, P = 0.003) and upper extremities (OR = 32.9, P = 0.041) had a higher odds of bleeding complications compared to head-and-neck flaps. Regression analysis also showed that older age is associated with bleeding complications, with patients aged 5-11 years (OR = 38.5, P = 0.027) and 12-17 years (OR = 30.6, P = 0.038) having greater rates compared to patients under the age of 2. The pediatric flap reoperation rate was found to be 3.6%-4.7%, with the highest flap anastomotic complication rate in the head-and-neck region (6.9%-8.0%).
Conclusion:
Free flap reconstruction across flap type, anatomic location, and age ranges are safe and efficacious in the pediatric population.
