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New Injection Site Dynamics of Insulin Lispro Discovered Through Photoacoustic Imaging

Arvind Kumar Jain1

  • 1Research & Development, Biological E. Limited, Hyderabad, India.

Journal of Diabetes Science and Technology
|October 14, 2022
PubMed
Abstract

No abstract available in PubMed .

Keywords:
diabetesinsulin diffusioninsulin lispropharmacokineticsphotoacoustic imaging

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Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
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