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Updated: Aug 25, 2025
Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
Published on: December 5, 2020
Investigation on bioactive metabolites produced by an endophytic fungus Trichoderma citrinoviride from the arils of
Xiaohui Kong1, Lin Xu2, Xiaokang Ji1
1The College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, People's Republic of China.
Abstract:
An endophytic fungus Trichoderma citrinoviride capable of producing active substances was isolated from the arils of Torreya grandis. Seven compounds were separated from the ethyl acetate extract of fermentation broth and mycelium by chromatography, respectively identified as trichomerol (1), bisorbicillinolide (2), sohirnone A (3), emodin (4), stigmasterol (5), ergosterol (6), daidzein (7). This study is the first to report of the isolation of the endophytic fungus T. citrinoviride from the arils of T. grandis with complete assignments of 1-7. Compound 1 and 2 exhibited significant antioxidant activity of diphenyl picryl hydrazinyl with IC50 38.92 and 3.91 µg/mL, respectively. Compound 1, 2, 4 and 7 significantly inhibited the growth of Staphylococcus aureus with MIC 0.78; 0.39; 0.20 and 0.20 mg/mL, respectively. Current study indicated the presence of endophytic fungus in the arils of Torreya grandis that could be responsible for the bioactive metabolite synthesis.
