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Updated: Aug 25, 2025

Analyzing Starvation-Induced Autophagy in the Drosophila melanogaster Larval Fat Body
Published on: August 4, 2022
Autophagy in cell fate decisions: knowledge gained from Drosophila
Camille Lacarrière-Keïta1, Sonya Nassari1, Steve Jean1
1Faculté de médecine et des sciences de la santé, Département d'immunologie et de biologie cellulaire, Université de Sherbrooke, 3201, Rue Jean-Mignault, Sherbrooke, QC J1E 4K8, Canada.
Abstract:
Autophagy is an important process that maintains adult tissue homeostasis and functions by protecting cells in autonomous and non-cell-autonomous ways. By degrading toxic components or proteins involved in cell signaling pathways, autophagy preserves the balance among stem cells, progenitors, and differentiated cells in various tissues. In this minireview, we discuss recent studies performed in Drosophila that highlight new roles of autophagy in adult cell fate decisions, including quiescence, proliferation, differentiation, and death.
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