A risk factor attention-based model for cardiovascular disease prediction

Yanlong Qiu1,2, Wei Wang3, Chengkun Wu4,5

  • 1Institute for Quantum Information and State Key Laboratory of High Performance Computing, College of Computer Science and Technology, National University of Defense Technology, 109 Deya Road, Changsha, 410073, People's Republic of China.

BMC Bioinformatics
|October 14, 2022
PubMed

Insights

This study introduces a novel Risk Factor Attention-based Model (RFAB) for predicting cardiovascular disease (CVD) using electronic medical records (EMR). The RFAB model significantly improves CVD prediction accuracy by integrating risk factors and patient data.

Area of Science:

  • Medical Informatics
  • Artificial Intelligence in Healthcare
  • Computational Medicine

Background:

  • Cardiovascular disease (CVD) is a leading cause of mortality, necessitating advanced diagnostic tools.
  • Electronic Medical Records (EMRs) contain valuable data for predicting CVD, but current NLP methods have limitations.
  • Automated CVD prediction from EMRs is crucial for intelligent diagnosis and treatment.

Purpose of the Study:

  • To develop an advanced model for predicting cardiovascular disease (CVD) using electronic medical records (EMRs).
  • To overcome the limitations of existing natural language processing (NLP) methods in CVD prediction.
  • To leverage both general EMR text and specific CVD risk factors for improved prediction accuracy.

Main Methods:

  • Proposed a Risk Factor Attention-based Model (RFAB) integrating deep neural network attention mechanisms.
  • Fused character sequences from EMR text with identified CVD risk factors.
  • Utilized BiLSTM-CRF model for risk factor identification, labeling category and time attributes.

Main Results:

  • The RFAB model demonstrated significant improvements in CVD prediction performance.
  • Achieved a high F-score of 0.9586, outperforming existing related methods.
  • Effectively utilized fine-grained information within EMRs for prediction.

Conclusions:

  • RFAB effectively utilizes 12 key CVD risk factors and their associated EMR information.
  • The model fuses risk factor details with character sequence information for accurate CVD prediction.
  • RFAB offers a reliable approach for CVD prediction by leveraging detailed EMR data.
Abstract

Related Concept Videos

Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
46
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
31
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
65
Factors affecting Blood pressure01:28

Factors affecting Blood pressure

Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
3.5K
Assessment of the Cardiovascular System I: Subjective Data01:23

Assessment of the Cardiovascular System I: Subjective Data

A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
424
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
20