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A risk factor attention-based model for cardiovascular disease prediction
Yanlong Qiu1,2, Wei Wang3, Chengkun Wu4,5
1Institute for Quantum Information and State Key Laboratory of High Performance Computing, College of Computer Science and Technology, National University of Defense Technology, 109 Deya Road, Changsha, 410073, People's Republic of China.
Insights
This study introduces a novel Risk Factor Attention-based Model (RFAB) for predicting cardiovascular disease (CVD) using electronic medical records (EMR). The RFAB model significantly improves CVD prediction accuracy by integrating risk factors and patient data.
Area of Science:
- Medical Informatics
- Artificial Intelligence in Healthcare
- Computational Medicine
Background:
- Cardiovascular disease (CVD) is a leading cause of mortality, necessitating advanced diagnostic tools.
- Electronic Medical Records (EMRs) contain valuable data for predicting CVD, but current NLP methods have limitations.
- Automated CVD prediction from EMRs is crucial for intelligent diagnosis and treatment.
Purpose of the Study:
- To develop an advanced model for predicting cardiovascular disease (CVD) using electronic medical records (EMRs).
- To overcome the limitations of existing natural language processing (NLP) methods in CVD prediction.
- To leverage both general EMR text and specific CVD risk factors for improved prediction accuracy.
Main Methods:
- Proposed a Risk Factor Attention-based Model (RFAB) integrating deep neural network attention mechanisms.
- Fused character sequences from EMR text with identified CVD risk factors.
- Utilized BiLSTM-CRF model for risk factor identification, labeling category and time attributes.
Main Results:
- The RFAB model demonstrated significant improvements in CVD prediction performance.
- Achieved a high F-score of 0.9586, outperforming existing related methods.
- Effectively utilized fine-grained information within EMRs for prediction.
Conclusions:
- RFAB effectively utilizes 12 key CVD risk factors and their associated EMR information.
- The model fuses risk factor details with character sequence information for accurate CVD prediction.
- RFAB offers a reliable approach for CVD prediction by leveraging detailed EMR data.
Background:
Cardiovascular disease (CVD) is a serious disease that endangers human health and is one of the main causes of death. Therefore, using the patient's electronic medical record (EMR) to predict CVD automatically has important application value in intelligent assisted diagnosis and treatment, and is a hot issue in intelligent medical research. However, existing methods based on natural language processing can only predict CVD according to the whole or part of the context information of EMR.
Results:
Given the deficiencies of the existing research on CVD prediction based on EMRs, this paper proposes a risk factor attention-based model (RFAB) to predict CVD by utilizing CVD risk factors and general EMRs text, which adopts the attention mechanism of a deep neural network to fuse the character sequence and CVD risk factors contained in EMRs text. The experimental results show that the proposed method can significantly improve the prediction performance of CVD, and the F-score reaches 0.9586, which outperforms the existing related methods.
Conclusions:
RFAB focuses on the key information in EMR that leads to CVD, that is, 12 risk factors. In the stage of risk factor identification and extraction, risk factors are labeled with category information and time attribute information by BiLSTM-CRF model. In the stage of CVD prediction, the information contained in risk factors and their labels is fused with the information of character sequence in EMR to predict CVD. RFAB makes well use of the fine-grained information contained in EMR, and also provides a reliable idea for predicting CVD.
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