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Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
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Enantioselective semisynthesis of novel cephalotaxine esters with potent antineoplastic activities against leukemia

Yujian Yang1, Qiuchun Yu2, Lean Hu1

  • 1Academy for Advanced Interdisciplinary Studies, Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, and Medi-X Pingshan, Southern University of Science and Technology, Shenzhen, 518000, China.

European Journal of Medicinal Chemistry
|October 15, 2022
PubMed

Keywords:
AntineoplasticsAsymmetric hydrogenationCephalotaxine-type alkaloidEnantioselective semisynthesisHomoharringtonineLeukemia

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