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Updated: Aug 25, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
Fusobacterium and Colorectal Cancer: Important Association or Random Coincidence?
Blake E Sanders1,2,3, Guanxi Qiao1,2,3, Jodi Hirschman1,2,3
1Dana-Farber Cancer Institute, Boston, Massachusetts.
None:
The role of the microbiome in human cancer has become an area of intensive research and controversy. Many reports have highlighted the physical association of Fusobacterium with colorectal cancer. This association has provided diagnostic and therapeutic promise but has also given rise to several controversies regarding the influence of Fusobacterium species on human colorectal cancer. Here, we discuss two areas of controversy surrounding this emerging pathogen: the influence of Fusobacterium on colorectal cancer proliferation and the effect of Fusobacterium on the immune microenvironment of colorectal cancer.

