Related Experiment Video
Updated: Aug 25, 2025

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Transhepatic device closure of atrial septal defect in children associated with interrupted inferior vena cava
Bhargavi Dhulipudi1, Shweta Bakhru1, Jagadeesh R Singh2
1Department of Paediatric Cardiology, Rainbow Children Heart Institute, Hyderabad, Telangana, India.
Insights
Transcatheter closure of fossa ovalis atrial septal defect (FOASD) is standard. A transhepatic approach offers a viable alternative for FOASD closure when the femoral venous route is impossible due to interrupted inferior vena cava (IVC).
Area of Science:
- Interventional Cardiology
- Congenital Heart Disease
- Vascular Access
Background:
- Percutaneous transcatheter closure is a standard treatment for fossa ovalis atrial septal defects (FOASD).
- Alternative access routes are necessary when the typical femoral venous approach is contraindicated, such as in cases of interrupted inferior vena cava (IVC) or occluded femoral veins.
- Transjugular, transhepatic, or surgical methods are potential alternatives for FOASD closure.
Purpose of the Study:
- To describe the successful application of a transhepatic approach for device closure of FOASD in patients with interrupted IVC.
- To present a case series demonstrating the feasibility and safety of this alternative technique.
Main Methods:
- Device closure of FOASD using a transhepatic venous access.
- Utilized percutaneous techniques for catheter and device delivery.
- Managed patients with interrupted inferior vena cava (IVC).
Main Results:
- Successful device closure of FOASD was achieved in two patients with interrupted IVC.
- The transhepatic approach was performed without any complications.
- Demonstrated the efficacy of the transhepatic route for FOASD closure in challenging anatomies.
Conclusions:
- Transhepatic device closure of FOASD is a safe and effective alternative when the transjugular or femoral venous approach is not feasible.
- This technique expands interventional options for patients with complex venous anatomy and FOASD.
- Highlights the adaptability of transcatheter techniques in congenital heart defect management.
Abstract:
Percutaneous transcatheter closure of fossa ovalis atrial septal defect (FOASD) is an established procedure. When femoral venous approach is unfeasible due to interrupted inferior vena cava (IVC) or occluded femoral veins, other interventional methods through transjugular, transhepatic approach, or surgical closure can be performed. We report two cases of transhepatic device closure of FOASD associated with IVC interruption successfully performed without any complications.
More Related Videos
08:00Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
Published on: June 15, 2015
07:41Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022