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Updated: Aug 25, 2025

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
07:41

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

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Rescue atrial septal defect closure with the new GORE® cardioform atrial septal defect occluder

Alessandra Pizzuto1, Magdalena Cuman1, Massimiliano Cantinotti1

  • 1Department of Pediatric Cardiology and GUCH Unit, Heart Hospital "G. Pasquinucci", National Research Council Tuscany Region "G. Monasterio", Massa, Italy.

Annals of Pediatric Cardiology
|October 17, 2022
PubMed

Insights

Atrioventricular block (AVB) is a rare complication of transcatheter closure of atrial septal defects (ASD). A novel device was successfully used to treat AVB after a previous device failed, offering a new treatment option.

Area of Science:

  • Cardiology
  • Medical Devices
  • Interventional Cardiology

Background:

  • Atrioventricular block (AVB) is a serious complication following transcatheter closure of atrial septal defects (ASD), occurring in 0.1%-6.2% of cases.
  • Defect anatomy, size, and device stiffness are implicated in AVB development.
  • The GORE® cardioform ASD occluder (GCA) presents a potential advancement in ASD treatment.

Observation:

  • A patient experienced complete AVB after ASD closure using an Amplatzer septal occluding device.
  • The initial occluding device was successfully retrieved percutaneously.
  • A GORE® cardioform ASD occluder (GCA) was subsequently deployed to treat the AVB.

Findings:

  • Percutaneous retrieval of an occluding device and rescue deployment of a GCA device can effectively manage complete AVB post-ASD closure.
  • This approach offers a viable alternative when initial device implantation leads to severe complications.

Implications:

  • The GCA device may provide a safer option for patients with challenging ASD anatomy or those who develop complications.
  • This case highlights the potential of device retrieval and replacement strategies in managing complications of transcatheter ASD closure.
  • Further research is warranted to evaluate the long-term efficacy and safety of the GCA device in complex ASD cases.

Keywords:
Atrial septal defectdeviceinterventional cardiac catheterization

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