Advanced Vision Analyzer-Virtual Reality Perimeter: Device Validation, Functional Correlation and Comparison with...

Area of Science:

• Ophthalmology
• Medical Technology
• Visual Field Testing

Background:

• Visual field testing is crucial for diagnosing and monitoring glaucoma and other optic nerve disorders.
• The Humphrey Field Analyzer (HFA) with its Swedish Interactive Threshold Algorithm (SITA) is a widely used standard for visual field assessment.
• Newer devices aim to provide comparable or improved accuracy and efficiency in visual field analysis.

Purpose of the Study:

• To evaluate the performance of the Advanced Vision Analyzer (AVA) by Elisar Vision Technology.
• To compare the pointwise threshold sensitivity and functional correlation of the Elisar Standard Algorithm (ESA) with the SITA algorithm of the HFA.

Main Methods:

• A prospective, cross-sectional study involving 160 eyes (85 control, 75 glaucoma patients) for functional assessment.
• Participants underwent both AVA (ESA) and HFA (SITA Standard 24-2) testing.
• Analyses included intraclass correlation coefficient (ICC), Bland-Altman plots, and linear regression to compare threshold measurements, test-retest variability (TRV), and blind spot accuracy.

Main Results:

• The AVA test duration was comparable to the HFA (7.08 vs. 6.26 minutes, P=0.228).
• Sectoral mean sensitivity showed statistically significant differences between AVA and HFA in both healthy and glaucoma participants (P < 0.001).
• Pointwise threshold values demonstrated moderate to strong correlations (r=0.68-0.89), and overall mean sensitivity showed good agreement (ICC=0.893).

Conclusions:

• The Advanced Vision Analyzer effectively captures visual field threshold values.
• Adequate functional correlation between AVA (ESA) and HFA (SITA Standard) suggests substantial equivalence.
• AVA shows potential for accurate visual field assessment, comparable to the HFA.