Effect of Coronavirus Disease-2019 Infection on Left Atrial Functions

Elif Ergül1, Ali Gökhan Özyildiz2, Nadir Emlek1

  • 1Department of Cardiology, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize, Turkey.

Insights

Patients who recovered from Coronavirus disease-2019 (COVID-19) showed impaired left atrial (LA) function. Echocardiography revealed significant differences in LA volumes and emptying fractions, indicating potential long-term cardiovascular risks.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Left atrial (LA) dysfunction is a significant risk factor for cardiovascular events.
  • Coronavirus disease-2019 (COVID-19) is a global pandemic with known cardiovascular implications.
  • The long-term effects of COVID-19 on cardiac function, particularly LA function, require further investigation.

Purpose of the Study:

  • To evaluate left atrial (LA) functions in patients who have recovered from COVID-19.
  • To compare LA function parameters between COVID-19 survivors and a healthy control group.

Main Methods:

  • A cohort of 60 COVID-19 recovered patients and 60 healthy controls were enrolled.
  • Echocardiography measurements were performed to assess cardiac function.
  • Demographic and echocardiographic characteristics were compared between the two groups.

Main Results:

  • COVID-19 survivors exhibited higher LA maximum volume (LAVmax) and LA pre-A volume, alongside a higher LA active emptying fraction.
  • A lower LA passive emptying fraction and decreased left ventricular ejection fraction were observed in the COVID-19 group.
  • Isovolumetric relaxation time was also reduced in patients recovered from COVID-19.

Conclusions:

  • Left atrial (LA) functions may be impaired in individuals following recovery from COVID-19 infection.
  • These findings suggest potential persistent cardiovascular sequelae after COVID-19.
  • Further research is warranted to understand the clinical significance and management of post-COVID-19 LA dysfunction.
Abstract

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