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Neonatal Outcome Associated With Maternal COVID-19 Infection in Adolescent Patients
Ana V Uzunov1, Diana C Secara2, Monica M Cirstoiu2
1Obstetrics and Gynaecology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, ROU.
Insights
COVID-19 infection in pregnant adolescents did not significantly impact neonatal outcomes like birth weight or Apgar scores. Adolescent pregnancy itself poses risks, but COVID-19 did not add further complications in this study.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
- Infectious Diseases in Pregnancy
Background:
- Pregnancy with Coronavirus disease 2019 (COVID-19) is linked to adverse outcomes like preeclampsia and preterm birth.
- Adolescent pregnancy is independently associated with increased maternal and neonatal risks.
- The combined risk of COVID-19 and adolescent pregnancy requires investigation.
Purpose of the Study:
- To determine if COVID-19 infection in pregnant adolescents poses additional risks to neonatal outcomes.
- To compare neonatal outcomes between COVID-19 positive and negative adolescent mothers.
Main Methods:
- A case-control study involving 17 COVID-19 positive adolescent mothers and 17 COVID-19 negative controls.
- Participants delivered between April 2020 and April 2022.
- Neonatal outcomes assessed included preterm birth, low birth weight, stillbirth, congenital anomalies, and Apgar scores.
Main Results:
- COVID-19 infection did not significantly affect newborn weight or Apgar scores in adolescent mothers.
- No statistically significant increase in preterm delivery was observed in COVID-19 positive adolescents.
- Congenital anomalies and stillbirth rates were not detailed in the provided results summary.
Conclusions:
- While adolescent pregnancy presents inherent risks, COVID-19 infection does not appear to exacerbate adverse neonatal outcomes in this population.
- Further research may be warranted to explore potential long-term effects or specific complications not captured in this study.
Abstract:
Background Coronavirus disease 2019 (COVID-19) infection during pregnancy has been associated with high rates of preeclampsia, stillbirth, and preterm birth. Adolescent pregnancy has also been associated with various adverse maternal and neonatal outcomes, including preeclampsia, stillbirth, preterm birth, congenital anomalies, and low birth weight. Therefore, this study aimed to determine whether COVID-19 infection associated with adolescent pregnancy represents an additional risk factor. Methods We performed a study that included 17 adolescent COVID-19- positive patients, who delivered in the Department of Obstetrics and Gynecology of University Emergency Hospital, Bucharest, between 01.04.2020 and 15.04.2022, and a control group of 17 patients who were COVID-19-negative and delivered in the same period in the same unit. In the control group, additional risk factors that could affect neonatal outcomes were excluded. The COVID-19 infection was confirmed using a polymerase chain reaction (PCR) test. The analysis of neonatal outcomes included preterm birth, low birth weight, stillbirth, congenital anomalies, and Apgar score calculated at one minute. Results The data from this study showed that COVID-19 infection does not influence the newborn's weight or Apgar score in adolescent patients. Also, in our study, COVID-19 infection was not statistically significant according to preterm delivery in adolescents. Conclusion Adolescent pregnancy represents an important health problem associated with a high risk of maternal and neonatal complications. However, COVID-19 infection does not influence neonatal outcomes in this population.
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