Peptide modification on the interior surface of red blood cell ghosts for construction of catalytic reactors
Related Experiment Video
Updated: Aug 25, 2025

Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols
Published on: January 2, 2013
Honoka Matsumoto1, Kentaro Okuichi1, Hiroshi Imamura1
1Department of Applied Chemistry, College of Life Sciences, Ritsumeikan University, 1-1-1, Noji-higashi, Kusatsu, Shiga, 525-8577, Japan. koshi@fc.ritsumei.ac.jp.
Abstract:
We have succeeded in in situ synthesis of gold nanoparticles (Au NPs) on the interior surfaces of red blood cell ghosts (RBCGs) with a cytoskeleton chemically conjugated to a gold-binding peptide. The Au NP-deposited RBCG with the peptide exhibits enhanced catalytic reactivity for the reduction of 4-nitrophenol due to the uniform distribution of the Au NPs on the inner surface and the coverage of the Au NPs surface with the peptide.

