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Aggregation of molecules is controlled in microdroplets.

Pallab Basuri1, Jenifer Shantha Kumar1, Keerthana Unni1

  • 1DST Unit of Nanoscience (DST UNS), Thematic Unit of Excellence (TUE), Department of Chemistry, Indian Institute of Technology Madras, Chennai 600036, India. pradeep@iitm.ac.in.

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Molecules de-aggregate at the air/water interface of microdroplets. Rapid solvent evaporation drives this molecular de-aggregation, leading to monomeric states at the interface and aggregated states in the core.

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Area of Science:

  • Physical Chemistry
  • Interface Science
  • Fluorescence Spectroscopy

Background:

  • Molecular aggregation affects fluorescence properties.
  • Microdroplets offer unique environments for studying molecular behavior.
  • Understanding interfacial phenomena is crucial in various chemical processes.

Purpose of the Study:

  • To investigate molecular de-aggregation at the air/water interface of microdroplets.
  • To explore the role of solvent evaporation in interfacial molecular organization.
  • To analyze the fluorescence behavior of dyes in microdroplet environments.

Main Methods:

  • Utilizing fluorescence microscopy to observe molecular states.
  • Employing various fluorescent dyes including Rhodamine 6G (R6G), Rhodamine B, acridine orange, and fluorescein.
  • Analyzing microdroplets formed from aqueous solutions of these dyes.

Main Results:

  • Dyes were found to be monomeric at the air/water interface.
  • Significant molecular aggregation was observed in the core of the microdroplets.
  • Aggregation-induced shifts in fluorescence confirmed the distinct molecular states.

Conclusions:

  • Molecular de-aggregation occurs at the air/water interface of microdroplets.
  • Rapid solvent evaporation is proposed as the mechanism driving interfacial de-aggregation.
  • The study highlights the influence of microenvironment and evaporation on molecular self-assembly.