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Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
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Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
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Antiviral Research: At age 41, a transition.

Mike Bray1

  • 1Antiviral Research, Chevy Chase, Maryland, USA.

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|October 17, 2022
PubMed
Summary

Antiviral Research celebrates 41 years, reviewing its growth in published papers and impact factor since 2011. The journal expanded its global editorial team and scope, covering diverse viral diseases and antiviral research.

Area of Science:

  • Virology
  • Pharmaceutical Research
  • Scientific Publishing

Background:

  • Antiviral Research (AVR) journal marks its 41st year with a leadership transition from Mike Bray to Subhash Vasudevan.
  • The journal reflects on its progress since 2011, building upon Erik De Clercq's initial 30-year review.
  • Editorial team expansion to 8 countries and increased female representation signify global reach and diversity.

Discussion:

  • AVR has seen a significant increase in published research on antiviral drugs, vaccines, and pathogenesis.
  • The journal covers a broad spectrum of viral diseases affecting both humans and livestock.
  • The impact factor has notably risen, reflecting enhanced scientific contribution and influence.

Key Insights:

  • The journal's scope has broadened, encompassing a wider array of viral threats and therapeutic strategies.

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  • Global collaboration and diversity within the editorial board have strengthened research dissemination.
  • Consistent growth in publications and impact factor underscore AVR's vital role in antiviral science.

    • Outlook:

    • Continued expansion of research into emerging and endemic viral diseases.
    • Further development of antiviral therapies and vaccine strategies.
    • Sustained commitment to high-impact publications in virology and infectious diseases.