Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Exosomes01:36

Overview of Exosomes

2.8K
Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
2.8K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electroactive Nanomaterials in Tissue Engineering: Advances, Mechanisms and Future Perspectives.

Advanced healthcare materials·2026
Same author

Skin-inspired cellulose-based hydrogel design with hydrophobic-conductive synergy for enhanced electrochemical nanoplastic removal.

Carbohydrate polymers·2026
Same author

Primary human intestinal organoids model enteric infection of monkeypox virus and enable scalable drug discovery.

Science advances·2026
Same author

Determination of optimal catheter insertion depth in totally implantable venous access ports via three-dimensional reconstruction of cervicothoracic veins: a cross-sectional retrospective analysis.

BMC surgery·2026
Same author

Graphene Oxide Nanosheets as Direct Photosensitizers for Photodynamic Therapy in a Size-Dependent Manner.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Different effects of polyethylene microplastics on bioaccumulation of three fungicides in maize (Zea mays L.).

Crop health·2026

Related Experiment Video

Updated: Aug 25, 2025

Author Spotlight: Standardizing and Improving the Extraction and Purification of Extracellular Vesicles from Human ADSCs
04:54

Author Spotlight: Standardizing and Improving the Extraction and Purification of Extracellular Vesicles from Human ADSCs

Published on: May 3, 2024

790

Exosomes as Potential Functional Nanomaterials for Tissue Engineering.

Yang Yao1, Yuhuan Jiang1, Jialu Song1

  • 1State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, No.14, Block 3, Renmin Road South, Chengdu, 610041, P. R. China.

Advanced Healthcare Materials
|October 17, 2022
PubMed
Summary
This summary is machine-generated.

Exosomes, tiny cell vesicles, show great promise in tissue engineering for regenerating tissues like bone and nerves. Research explores modifying exosomes for targeted delivery in regenerative medicine.

Keywords:
exosomesnanoparticlesregenerative medicinetargeted deliverytissue engineering

More Related Videos

Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts
06:27

Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts

Published on: May 16, 2020

3.5K
Preparation of Exosomes for siRNA Delivery to Cancer Cells
09:59

Preparation of Exosomes for siRNA Delivery to Cancer Cells

Published on: December 5, 2018

25.3K

Related Experiment Videos

Last Updated: Aug 25, 2025

Author Spotlight: Standardizing and Improving the Extraction and Purification of Extracellular Vesicles from Human ADSCs
04:54

Author Spotlight: Standardizing and Improving the Extraction and Purification of Extracellular Vesicles from Human ADSCs

Published on: May 3, 2024

790
Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts
06:27

Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts

Published on: May 16, 2020

3.5K
Preparation of Exosomes for siRNA Delivery to Cancer Cells
09:59

Preparation of Exosomes for siRNA Delivery to Cancer Cells

Published on: December 5, 2018

25.3K

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Nanotechnology

Background:

  • Exosomes are nanoscale extracellular vesicles (40-160 nm) involved in intercellular communication.
  • They function as natural nanomaterials, carrying diverse biomolecules.
  • Exosomes hold significant potential for drug delivery and therapeutic applications.

Purpose of the Study:

  • To review the applications of exosomes in tissue engineering.
  • To highlight progress in exosome-mediated tissue regeneration.
  • To discuss exosome modification strategies and future directions.

Main Methods:

  • Literature review of exosome applications in tissue engineering.
  • Summary of exosome modification techniques for targeted delivery.
  • Analysis of current challenges and future prospects.

Main Results:

  • Exosomes are actively investigated for regenerating various tissues, including the central nervous system, kidney, bone, cartilage, heart, and endodontium.
  • Exosome modification enhances targeting capabilities for therapeutic delivery.
  • Significant advancements have been made in utilizing exosomes for regenerative purposes.

Conclusions:

  • Exosomes represent a promising frontier in tissue engineering and regenerative medicine.
  • Further research into exosome modification and application is warranted.
  • Exosomes offer a versatile platform for developing advanced therapeutic strategies.