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Aerobic exercises and cognitive function in post-stroke patients: A systematic review with meta-analysis
Xiaogang Li1,2, Di Geng3, Siyue Wang3
1Chengdu Sport University, Chengdu, Sichuan Province, China.
Medicine
|October 18, 2022
Summary
Aerobic exercise significantly improves global cognitive function in post-stroke patients. Moderate-intensity aerobic exercise interventions yield the greatest cognitive benefits for stroke survivors.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Exercise Science
Background:
- Stroke frequently leads to cognitive impairment, affecting patients' quality of life.
- Identifying effective interventions to improve post-stroke cognitive function is crucial for rehabilitation.
Purpose of the Study:
- To evaluate the impact of aerobic exercise on cognitive function in post-stroke patients.
- To determine specific aerobic exercise parameters that maximize cognitive benefits.
Main Methods:
- Systematic review and meta-analysis of randomized controlled trials (RCTs) adhering to PRISMA guidelines.
- Searched major databases including PubMed, Web of Science, EMBASE, and Cochrane Library.
- Assessed study quality using the Cochrane risk of bias tool and analyzed data with Review Manager 5.4.1.
Main Results:
- Eleven RCTs involving post-stroke patients were included.
- Aerobic exercise significantly improved global cognitive ability (SMD = 0.51, P = .004).
- Moderate-intensity exercise demonstrated the largest effect size for global cognition (SMD = 0.98, P = .0001).
Conclusions:
- Aerobic exercise is beneficial for enhancing cognitive function in post-stroke patients.
- Moderate-intensity aerobic exercise appears most effective for improving global cognition.
- No significant improvements were observed in cognitive flexibility, working memory, selective attention, or conflict resolution.
