Related Experiment Video
Updated: Aug 25, 2025

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods
Published on: March 10, 2020
Effect of comprehensive nursing intervention for congenital heart disease in children: A meta-analysis
Xueying Ding1, Jiaxuan Wen1, Xinxin Yue1
1School of Nursing, Weifang Medical University, Weifang , Shandong province, China.
Insights
Comprehensive nursing interventions significantly improve perioperative outcomes for children with congenital heart disease (CHD). These interventions reduce hospital stays, lower complication risks, and decrease anxiety and pain, enhancing overall care.
Area of Science:
- Pediatric Nursing
- Cardiology
- Healthcare Management
Background:
- Congenital heart disease (CHD) presents unique challenges for pediatric patients undergoing surgery.
- Perioperative care for children with CHD requires specialized nursing interventions to optimize outcomes.
- Existing literature suggests various nursing approaches may impact surgical recovery, but a consolidated analysis is needed.
Purpose of the Study:
- To systematically evaluate the effectiveness of comprehensive nursing interventions on perioperative outcomes in children with CHD.
- To assess the impact of interventions such as educational support, empathic interviewing, motor exercise, and therapeutic play.
- To quantify effects on hospital stay, complication rates, parental satisfaction, anxiety, and pain.
Main Methods:
- A comprehensive meta-analysis was conducted, searching multiple databases (PubMed, Embase, Web of Science, Scopus, Cochrane, etc.) up to August 2021.
- The study followed Cochrane Handbook and PRISMA guidelines for systematic reviews and meta-analyses.
- Data analysis was performed using RevMan 5.4 and Stata 16.0 to synthesize findings.
Main Results:
- Comprehensive nursing interventions significantly reduced length of hospital stay (WMD = -1.982, P < .001) and the risk of post-operative complications (OR = 0.345, P < .001).
- Interventions led to increased parental satisfaction (OR = 0.308, P < .001) and notably decreased preoperative anxiety (WMD = -6.721, P < .001) and postoperative pain (WMD = -7.103, P < .001).
Conclusions:
- This meta-analysis confirms that comprehensive nursing interventions yield significant benefits for children with CHD during the perioperative period.
- Key improvements include reduced complication rates, shorter hospital stays, and enhanced patient and parental well-being through decreased anxiety and pain.
- The findings strongly support the integration of comprehensive nursing care strategies to improve clinical outcomes for pediatric CHD patients.
Objectives:
This meta-analysis aimed to assess the impact of nursing interventions (e.g., educational and empathic interviewing, motor exercise, therapeutic play interventions) on the perioperative outcome of children with congenital heart disease (CHD).
Methods:
We searched PubMed, Embase, Web of Science, Scopus, Cochrane, EBSCO, The Chinese National Knowledge Infrastructure, Wan Fang Data and the VIP Chinese Journal Service platform from the date of database creation to August 2021. Our study adhered to the recommendations of the Cochrane Handbook and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. RevMan 5.4 and Stata 16.0 were used to complete the meta-analysis.
Results:
This meta-analysis showed that comprehensive nursing intervention reduced both the length of hospital stay (weighted mean difference [WMD] = -1.982, 95%CI [-2.329, -1.634], P < .001) and the related risk of post-operative complications [OR = 0.345, 95%CI (0.225, 0.528), P < .001]. In addition, nursing intervention increased parental satisfaction with the care provided [OR = 0.308, 95%CI (1.923, 6.863), P < .001]. Nursing interventions have also had a positive impact in reducing preoperative anxiety [WMD = -6.721, 95% CI (-7.194, -6.249), P < .001] and postoperative pain [WMD = -7.103, 95% CI (-7.103, -7.663), P < .001] in children.
Conclusions:
This meta-analysis confirms the beneficial effects of comprehensive nursing interventions in terms of reduced complication rates and shorter hospital stays. The effectiveness of comprehensive nursing in reducing anxiety and pain levels was also demonstrated. The findings support the implementation of comprehensive care interventions in the perioperative period for children with CHD to improve clinical outcomes.
Related Concept Videos
Mitral Stenosis IV: Nursing Management
Heart Failure VII: Nursing Interventions
Rheumatic Heart Disease IV: Nursing Management
Mitral Regurgitation IV: Nursing Management
Angina V: Nursing Management
Cardiomyopathy VI: Nursing Management

