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Related Experiment Video

Updated: Aug 25, 2025

Orthotopic Injection of Breast Cancer Cells into the Mice Mammary Fat Pad
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Ectopic breast carcinoma.

Georgios-Ioannis Verras1, Francesk Mulita1, Levan Tchabashvili1

  • 1Department of Surgery, Breast Unit, University Hospital of Patras, Patras, Greece.

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|October 18, 2022
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Summary

Carcinoma of accessory breast tissue (CABT) is rare, but vigilance is key. Surgical excision with axillary lymph node dissection is a justified approach for this rare breast malignancy.

Keywords:
accessory breast tissuebreast cancerectopic malignancy

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Pathology

Background:

  • Carcinoma of accessory breast tissue (CABT) is an exceptionally rare malignancy, accounting for only 0.3% of all breast cancers.
  • Ectopic breast tissue, while infrequent, necessitates awareness due to the potential for malignant transformation.

Observation:

  • A 65-year-old postmenopausal woman presented with a painful, growing mass in her right axilla.
  • Physical examination revealed a 3 cm mass infiltrating the skin, with no palpable lesions in the breast itself.
  • Core biopsy confirmed Nottingham Grade II NST invasive breast carcinoma.

Findings:

  • The patient underwent successful breast-conserving surgery and axillary lymph node dissection (ALND).
  • Surgical technique prioritized preservation of the axillary vein and long thoracic nerve.
  • Skin flaps were mobilized for optimal cosmetic closure of the axillary incision.

Implications:

  • This case underscores the importance of vigilance for CABT in clinical practice.
  • Further large-scale epidemiological studies are needed to establish definitive management guidelines and prognostic factors for CABT.
  • Current evidence supports surgical excision and ALND as a reasonable treatment for CABT in the absence of established protocols.