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Updated: Aug 25, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Reducing care time after implementing protocols for acute ischemic stroke: a systematic review.
Karina Fonseca de Souza Leite1, Samuel Ribeiro Dos Santos1, Rubia Laine de Paula Andrade1
1Universidade de São Paulo, Escola de Enfermagem de Ribeirão Preto, Departamento de Enfermagem Materno-Infantil e Saúde Pública, Ribeirão Preto SP, Brazil.
Implementing acute ischemic stroke protocols improves in-hospital care times. However, faster symptom recognition in prehospital settings is crucial for better outcomes in acute ischemic stroke patients.
Area of Science:
- Neurology
- Emergency Medicine
- Health Services Research
Background:
- Acute ischemic stroke treatment necessitates rapid intervention and symptom recognition.
- Cerebral reperfusion therapy is a critical component of acute ischemic stroke management.
- Timely care significantly impacts patient outcomes in stroke cases.
Purpose of the Study:
- To evaluate the effectiveness of acute ischemic stroke protocols in reducing patient care times.
- To analyze the impact of implementing standardized protocols on stroke treatment efficiency.
- To identify key time intervals affected by stroke protocol implementation.
Main Methods:
- Systematic review of primary studies published between 2011 and 2020.
- Inclusion of studies in Portuguese, English, and Spanish focusing on acute ischemic stroke.
- Data extraction and narrative synthesis by independent reviewers, with methodological quality assessment.
Main Results:
- Thirty-five studies were included out of 11,226 initial publications.
- Protocol implementation showed effectiveness in improving door-to-image, image-to-needle, and door-to-needle times.
- Limited improvement was noted in symptom-onset-to-door time; study population clarity was a limitation.
Conclusions:
- Protocol implementation has led to significant advances in in-hospital stroke care.
- Enhanced prehospital care and earlier symptom recognition are essential for optimizing stroke treatment.
- Further research is needed to address limitations in defining the study population for stroke protocol effectiveness.
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