Cationic Modified PVA Hydrogels Provide Low Friction and Excellent Mechanical Properties for Potential Cartilage and
Yuru Chen1,2, Jian Song3, Song Wang4
1Department of Mechanical Engineering, Tsinghua University, 100084, Beijing, China.
Abstract:
Poly(vinyl alcohol) (PVA) hydrogel is a promising candidate for articular cartilage repair yet restrained by its mechanical strength and tribological property. Current work reports a newly designed PVA-based hydrogel modified by glycerol (g), bacterial cellulose (BC), and a cationic polymer poly (diallyl dimethylammonium chloride) (PDMDAAC), which is a novel cationic strengthening choice. The resultant PVA-g-BC-PDMDAAC hydrogel proves the effectiveness of this modification scheme, with a confined compressive modulus of 19.56 MPa and a friction coefficient of 0.057 at a joint-equivalent load and low sliding speed. The water content, swelling property, and creep behavior of this hydrogel are also within a cartilage-mimetic range. The properties of PVA-based hydrogels before PDMDAAC addition are likewise studied as a cross-reference. Besides, PDMDAAC-modified PVA hydrogel realizes ideal mechanical and lubrication properties with a relatively low PVA concentration (10 wt.%) and facile fabrication process, which lays a foundation for mass production and marketization in the future.
